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M S Sands Selected Research

Mucopolysaccharidosis VII (Sly Syndrome)

4/2007Clinical response to persistent, low-level beta-glucuronidase expression in the murine model of mucopolysaccharidosis type VII.
2/2002Abnormal osteoclast morphology and bone remodeling in a murine model of a lysosomal storage disease.
11/2001Biodistribution, kinetics, and efficacy of highly phosphorylated and non-phosphorylated beta-glucuronidase in the murine model of mucopolysaccharidosis VII.
9/2001Prevention of systemic clinical disease in MPS VII mice following AAV-mediated neonatal gene transfer.
3/2001Intracranial injection of recombinant adeno-associated virus improves cognitive function in a murine model of mucopolysaccharidosis type VII.
3/2001A novel model of murine mucopolysaccharidosis type VII due to an intracisternal a particle element transposition into the beta-glucuronidase gene: clinical and pathologic findings.
12/2000Gene transfer of low levels of beta-glucuronidase corrects hepatic lysosomal storage in a large animal model of mucopolysaccharidosis VII.
10/2000Treatment of a lysosomal storage disease, mucopolysaccharidosis VII, with microencapsulated recombinant cells.
9/2000Delivery of a retroviral vector expressing human beta-glucuronidase to the liver and spleen decreases lysosomal storage in mucopolysaccharidosis VII mice.

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M S Sands Research Topics

Disease

10Lysosomal Storage Diseases (Lysosomal Storage Disease)
09/2013 - 10/2000
9Mucopolysaccharidosis VII (Sly Syndrome)
04/2007 - 09/2000
4Mucopolysaccharidoses
09/2001 - 11/2000
2Disease Progression
04/2007 - 09/2001
1Vitamin D Deficiency
01/2020
1Hypertension (High Blood Pressure)
01/2020
1Inflammation (Inflammations)
01/2020
1Central Nervous System Diseases (CNS Diseases)
01/2014
1Mucopolysaccharidosis III (Sanfilippo Syndrome)
09/2013
1Stroke (Strokes)
09/2010
1Hearing Loss (Hearing Impairment)
11/2001
1Neoplasms (Cancer)
09/2001
1Acute-Phase Reaction
03/2001
1Hemophilia A (Haemophilia)
03/2001
1Intellectual Disability (Idiocy)
03/2001
1Catastrophic Illness
10/2000
1Leukemia
09/2000

Drug/Important Bio-Agent (IBA)

9GlucuronidaseIBA
04/2007 - 09/2000
6EnzymesIBA
04/2007 - 10/2000
5GlycosaminoglycansIBA
02/2002 - 09/2000
1ReninIBA
01/2020
1Vitamin DFDA LinkGeneric
01/2020
1Calcitriol Receptors (Calcitriol Receptor)IBA
01/2020
1Hexosaminidases (Hexosaminidase)IBA
09/2013
1alpha-N-acetyl-D-glucosaminidase (alpha-N-acetylglucosaminidase)IBA
09/2013
1DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
09/2010
1Actins (F Actin)IBA
03/2001
1LipopolysaccharidesIBA
03/2001
1AntibodiesIBA
03/2001
1HydrolasesIBA
11/2000
1AcidsIBA
11/2000
1Retinal Pigments (Pigments, Visual)IBA
11/2000
1Retinaldehyde (Retinal)IBA
11/2000
1Complementary DNA (cDNA)IBA
09/2000
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
09/2000

Therapy/Procedure

4Therapeutics
01/2014 - 10/2000
3Bone Marrow Transplantation (Transplantation, Bone Marrow)
09/2001 - 11/2000
2Enzyme Replacement Therapy
11/2001 - 09/2001
1Investigational Therapies (Experimental Therapy)
03/2001